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While animal studies extending to 6 weeks have found no concerning signals, humans using the peptide are essentially participating in uncontrolled self-experimentation regarding long-term outcomes

Recalls & Warnings September 05, 2014 Seller of "Nerve", "Cleanse" and Probiotic Supplements Warned for Drug Claims On July 30, 2014, the FDA issued a warning letter to Plexus Worldwide, Inc., following a review of the company's website and product labels, which found statements made about Fast Relief, BioCleanse and ProBio5 to be drug claims

however, it is prepared in accordance with current good manufacturing practices and quality standards applicable to outsourcing facilities