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Many of these applications are difficult to achieve due to cofactor inactivation in complex biological environments and cofactor-induced cellular stress

Raghavan et al., 2000)

(5) This may be due to the potential role of AOD 9604 in cellular differentiation processes and, potentially, in the synthesis of proteins important for tissue repair

Overall, our binding analysis and Th-T assays of Syn 1103 with various interactors tested suggest that random cellular proteins are sequestered within inclusions due to the promiscuous binding nature of Syn 1103 , rather than exerting any inhibitory effect on its aggregation