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10.3389/fphar.2022.929262 Summary Keywords trimethylamine N-oxide, gut microbiota, chronic diseases, traditional Chinese medicine, inflammation, oxidative stress, metabolic disorders Citation Qin Z, Wu W, Yang X, Wang X, Ding A, Huang Y, Tang J, Jiang S, Zhang P, Qian C, Zhang X, Zhou S, Wang Y, Song Z, Sun M, Wang M, Shen S and Zhu B (2025) The role of trimethylamine N-oxide in disease pathogenesis and the therapeutic potential of traditional Chinese medicine