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Scenario one: PCAC recommends inclusion on the bulks list

This implies that it is only to be used once and should be thrown away after opening, even if there is still water in the vial

While PD-1 expression in T cells (CD4+ and CD8 + ) resulted unchanged (Supplementary Figure 3), I2-treated tumors revealed a reduced expression of PD-L1 in the monocytic myeloid-derived suppressor cell (M-MDSC) subset monocytes and in tumor-associated macrophages (TAM) (Fig