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Together, these findings demonstrate that ARF-BP1, PAM and FBXL3 are critical E3 ligases that regulate REV-ERB degradation to maintain the stability and timing of circadian clock gene expression (Shi et al., 2013

Moreover, translation strategies usually require innovation in the laboratory that must be supported by the pillars of evidence-based medicine for predictable regulatory outcomes

Noninvasive in vivo imaging of diabetes-induced renal oxidative stress and response to therapy using hyperpolarized 13C dehydroascorbate magnetic resonance

This approach is effective in the treatment of several CNS disorders by enhancing drug delivery, bioavailability and efficacy