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Interestingly, some recent studies determined that the endothelial cell-derived exosomes indeed contained MT proteins responding to cellular stress conditions and EVs from various cells or human samples exhibited the presence of zinc transporters as well 111

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n = 6 for each condition from three independent experiments

Specifically, -syn pathology not only directly impairs mitochondrial function and activates neuroinflammation, but its own aggregation process is also markedly promoted by OS and inflammatory environments [46]