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Transposable elements can be directly associated with a number of diseases, such as hemophilia (which could be considered as the prototype for a disease-causing insertion), muscular dystrophy, various types of cancer [60] (cancers of the pancreas, colon, ovaries [59], breast [61], bladder [62], liver [63], B-cell non-Hodgkin lymphoma [64]), senescence of mesenchymal progenitor cells [65], amyotropic lateral sclerosis [61], Alzheimers disease, Parkinsons disease, Huntingtons disease, Friedreich ataxia, Fragile X Syndrome, Fronto-temporal lobar degeneration, multiple sclerosis, AicardiGoutires syndrome, Autism spectrum disorders, mental disorders (schizophrenia, bipolar disorder, major depressive disorder, post-traumatic stress disorder), CreutzfeldtJakob disease, neurofibromatosis type I [66]

Current applications : Anti-aging, healing, inflammation, skin health

[DOI] [PubMed] [Google Scholar] 452.Nath D., Banerjee P

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