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doi: 10.3389/fphar.2022.1077468

As a co-factor in carboxylase enzymes, Biotin is involved in gluconeogenesis, fatty acid synthesis, and the metabolism of amino acids

Moliteo et al., 2022

This generally is not critical in testing male Caucasians, but it certainly is a problem in diagnosing some Caucasian females and blacks of both sexes, especially during the reticulocytosis following acute hemolysis