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250,251,252,253 Aspirin is synthesized through the esterification of salicylic acid with acetic anhydride, a process catalyzed by sulfuric acid

Nature 460 , 392395 (2009)

[4] [6] The direct delivery of ascorbic acid into the bloodstream allows for supraphysiological concentrations, which could have distinct biological effects, such as pro-oxidant activity in the presence of transition metals or selective cytotoxicity against certain malignant cells, although these applications remain under investigation and are not universally accepted as standard of care