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1):2021 Franssen LE, Stege CAM, Zweegman S, van de Donk N, Nijhof IS (2020) Resistance mechanisms towards CD38-directed antibody therapy in multiple myeloma

One of the major drawbacks is their large molecular mass of about 150 kDa, responsible for slow kinetics and limited tumor penetration with only approximately 20% of the administered dose reaching the tumor site [85]

If the patient is suffering from trigeminal neuralgia, the physician can order a magnetic resonance imaging (MRI) scan to look for the blood vessel compressing the nerve or to rule out multiple sclerosis or a tumor as the cause of trigeminal neuralgia

doi: 10.1055/s-2000-8470 42