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doi: 10.1016/j.intimp.2024.112819

2012, Zhou et al., Ferrari et al

Central to this process is the activation of profibrotic cytokines, such as transforming growth factor-beta (TGF-), as well as the activation of fibroblasts and peritubular myoid cells, which secrete abnormal amounts of collagen types I, III, and IV, along with fibronectin (Xiao et al., 2022)

Such differential expression patterns may enable localized sensing of metabolite gradients and redox cues, linking GLR activity to tissue-specific metabolic regulation