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We demonstrate that -catenin forms a complex with Jun Dimerization Protein 2 (JDP2) and arginine methyltransferase 5 (PRMT5) that elicit histone H3R2me1/H3R2me2s-induced transcriptional activation via a TCF-independent mechanism, by recruitment of WD repeat domain 5 (WDR5)/myeloid/lymphoid or mixed-lineage leukemia protein (MLL) methyltransferase complexes at the promoters of multiple genes in the GSH-metabolic cascade

Conversely, the overexpression of Chac2 (OE-Chac2) in HL60 cells (Fig

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As a sympathomimetic amine, phentermine directly stimulates the release of norepinephrine and can cause significant heart rate increases, blood pressure elevation, and pronounced palpitations