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This is particularly important for expensive peptides, discontinued products, or compounds with long lead times for replacement

It is also very stable when exposed to heat or acid and is highly safe. Discovery of the Ergothioneine Transporter The primary reason that EGT has received attention in recent years is due to the discovery in 2005 of the ergothioneine transporter (ETT) for the uptake of EGT into cells in humans. As mentioned above, only some microorganisms can produce EGT, but it is now known that EGT is used via ETT in various lifeforms including plants, fish, and mammals

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However, following ingestion of a large overdose (150 mg/kg or greater) the glucuronide and sulfate conjugation pathways are saturated resulting in a larger fraction of the drug being metabolized via the P-450 pathway