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SNCA A53T and Gpx4 fl/fl were crossbred to obtain SNCA A53T / Gpx4 +/fl double transgenic hemizygous mice

doi: 10.1016/j.cell.2016.05.039 185 MatheoudDCannonTVoisinAPenttinenA-MRametLFahmyAMet al

Cartilage and osteoarthritis models published research has explored AOD-9604 in articular cartilage and chondrocyte models, sometimes in combination with HA or other matrix peptides