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Canadian Journal of Diabetes

Once aroused, pDCs unleash a generous surge of interferon-alpha (IFN-), setting the stage for cutaneous myeloid dendritic cell (mDC) activation

The synthetic version was developed to provide a more stable and standardized research compound compared to the natural extract

To measure degranulation, 0.2 g of antibody per well of APC-anti-CD107a (clone H4A3, BioLegend) and FITC-anti-CD56 antibody (HCD56, BioLegend) were added directly to the wells at the beginning of the co-culture