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Furthermore, pinocembrin has been found to suppress oxidized low-density lipoprotein-activated NLRP3 inflammasome and GSDMD-facilitated endothelial cell pyroptosis via an Nrf2-dependent signaling pathway [176]

Mutant libraries reveal negative design shielding proteins from supramolecular self-assembly and relocalization in cells

110 Recent studies suggest that KAT8 may mediate PCK2K100 lactylation, promoting hepatic ferroptosis and ischemia-reperfusion injury in patients with hyperlactatemia during liver transplantation