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Nature 373: 699702 [DOI] [PubMed] [Google Scholar] Schmidt L., Duh F.M., Chen F., Kishida T., Glenn G., Choyke P., et al

It is a mandatory cofactor for the enzymes that stabilize and cross-link collagen, the bodys most abundant protein, which is found in skin, bones, cartilage, and blood vessels

The Risks at This Scale Stage-gates pushed back Competitors presenting IO insights first at AACR Extra reproducibility cycles from governance CRO data needing days of harmonization Spatial + transcriptomic signals buried across systems What Lena Needed Not a massive overhaul just a unified way to work: Imaging + omics + context accessible together Reproducible workflows across sites Biomarkers ready before governance reviews Less reliance on a single SME maintaining legacy pipelines Cleaner handoffs to translational, clinical, and regulatory The Quiet Shift She evaluated and quickly implemented a more governed, unified workflow on one key IO program