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Through the control of the Fenton reaction, iron chelators such as deferoxamine chelate iron and halt lipid peroxidation

Another recurring limitation emerges on antioxidant-based interventions in ASD, constrained by a fundamental methodological gap: most clinical studies report behavioral or functional improvements without directly measuring oxidative-stress biomarkers

The interaction between aPL and targets like 2GPI triggers the activation of endothelial cells, platelets, monocytes, and neutrophils, as well as the complement and coagulation systems, forming a key molecular mechanism underlying APS pathogenesis (Knight and Erkan, 2024)

Sci Rep 7 , 13828 (2017)