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Analysis of variance (ANOVA) and Duncan's multiple range test were used to locate differences, and the sperm quality and motility parameters, plasma membrane integrity, and acrosome integrity were compared between groups

IGF1R inhibitors such as IMC-A12 and picropodophyllin effectively suppress GBM growth in preclinical models, reducing tumor proliferation and angiogenesis

4 Conclusion Patients with underlying liver disease should avoid combined use of antipsychotic medications, implement precise medication management, and strengthen liver function monitoring