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14 Low B12 and/or low folate are both risk factors for high homocysteine, which is common in people with MTHFR mutations

Prevalence of vitamin B12 deficiency in pregnancy Certainly not everyone is deficient in vitamin B12, and deficiency rates vary widely in different parts of the world depending on food availability and dietary practices

Guidelines for Administration to Children In children, the dose is adjusted based on their weight and stage of development to avoid giving too much medication while still ensuring it works effectively

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