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Understanding Glutathione Role of Glutathione in Cellular Function and Detoxification: Glutathione acts as a critical protector against oxidative stress, enabling cells to neutralize free radicals that can lead to chronic diseases

EMBO J (2000) 19(18):497685.10.1093/emboj/19.18.4976 2 LiuSCaiXWuJCongQChenXLiTet alPhosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation

The discrepancy, discussed above, between the results obtained for the cortex and hippocampus is probably due to the high level of antioxidant enzyme expression in the cortex, which cushions the impact of increased levels of highly oxidizing molecules, thus giving the cortex an advantage over the hippocampus in limiting oxidative stress (Sharma et al., 2013)