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Sep 18 2023;108(10):2447-2469

Recent studies have demonstrated that the relationship between the ciliary muscle and TM function changes in morphology, causing a change in TM micro skeleton, increased outflow resistance, and IOP elevation in glaucoma

To address these challenges, future research should integrate multi-omics approaches to delineate the distinct functions of individual PRLM subtypes, develop precision delivery strategies targeting receptorligand interactions, and evaluate their efficacy and safety in early phase clinical trials