lippard glutathione cisplatin

lippard glutathione cisplatin Intracellular glutathione-depleting polymeric micelles for prodrug delivery to overcome cisplatin resistance of cancers Frontiers | Studies on the

Name: lippard glutathione cisplatin Intracellular glutathione-depleting polymeric micelles for prodrug delivery to overcome cisplatin resistance of cancers Frontiers | Studies on the
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Frontiers Studies on the mechanism of ototoxic action of cisplatin and the antagonistic effect of polyphenolic compounds Overcoming resistance to cisplatin by inhibition of glutathione S transferases (GSTs) with ethacraplatin micelles in vitro and in vivo ScienceDirect Role of glutathione S transferase Pi in cisplatin induced nephrotoxicity ScienceDirect Schematic diagram of GSH related elimination of cisplatin and of Download Scientific Diagram

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The molecular mechanisms could be the inhibition of the expression of apoptosis-related proteins BCL2-Associated X (BAX), Caspase-3 (CASP3), and poly ADP-ribose polymerase (PARP)

Guan, X., Hoffman, B., Dwivedi, C

The studies revealed that after 15 min at pH 7.8 with 25-fold excess BCPB and 250-fold excess of TCEP the reaction was completed with respect to thiol analytes