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Because secretagogues amplify natural GH pulses rather than creating a pharmacokinetic peak from outside, dosing in the evening (near sleep onset) aligns the induced pulse with the body's largest natural nocturnal GH surge

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[1] [3] The unique aspect of this formulation lies in its high concentration and the option for preservative-free preparation, which may be suitable for patients with sensitivities or allergies to common preservatives