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In high-transmission areas, malaria is one of the most common indications for blood transfusion, yet transfusion thresholds in severe malaria management remain uncertain ( Classical theories attribute malarial anemia to three primary mechanisms: direct parasite lysis of infected red blood cells (RBCs)

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Final coordinates and structure factors have been submitted to the RCSB and assigned accession codes 6ECA, 6EC6, 6ED2, and 6ED1 for the Lr GUS, Rg GUS, Fp GUS, and Bd GUS structures, respectively

This synthetic approach is relevant when aiming to conjugate two entities to an oligonucleotide as exemplified recently in the work of Aartsma-Rus and coworkers: conjugation of a homing peptide and a cell-penetrating peptide allows for increased targeted tissue delivery of a morpholino oligomer as compared to the conjugation of a single peptide 34