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The enzyme is complex, with four copper atoms, two or more disulfides, glycosylation, optimal activity at acidic pH (pH 45) and an electron transfer pathway that is strongly interrupted by modest concentrations of hydroxyl anions or halides (for example, NaCl and KCl) in cell culture media 21

For instance methylcobalamin can enhance nerve function and reduce neuropathy symptoms whereas cyanocobalamin has not shown a substantial effect, on nerve function

Based on the findings, it was concluded that the E7 compound exhibited anti-Parkinson activity which was more evident at 30 mg/kg oral dose as evaluated by the haloperidol-induced animal model of mice

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