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Method validation revealed a satisfactory linearity ( R 2 0.999), accuracy (recovery: 92.18102.85%), and precision (relative standard deviation 1.91%), with the limits of detection (for 100 g of product) being 0.26 and 0.15 g for reduced glutathione and oxidized glutathione, respectively

For the genes involved in the tissue-sharing microbiome regulation, pathways related to cell cycle, development, and metabolism show the highest frequency in the GO analysis, while pathways pertaining to metabolism, transport, and localization are among the top terms in the tissue-specific regulatory groups (Fig