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Though not examined in this study, NO has been shown to inhibit NOX activity through s-nitrosylation

Brain Behav

Consequently, riboflavin may significantly enhance cell longevity by boosting the activity and concentration of antioxidant enzymes, such as superoxide dismutase, catalase, and glutathione peroxidase, that act on deactivating peroxides, which may create an oxidant environment (43)