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162 Furthermore, although it has been shown to improve pain, fatigue, depression, and sleep quality in the short term, long-term cyclobenzaprine has been found to be no more effective than placebo for treating fibromyalgia and other chronic pain conditions

One honest caveat up front, because it shapes everything below: the evidence base for 5-Amino-1MQ is almost entirely preclinical mouse and cell-culture studies

However, the true contribution of dietary methionine excess, which hasn't been specifically investigated in large-scale epidemiologic studies, may represent an alternative cause of moderate hyperhomocysteinemia

(3) In other words, your liver dumps toxins into the gut, and instead of getting rid of them, your body takes them right back in