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Masses correspond to the expected products were detected in all samples except those with l-His as the negative control (Supplementary Fig

The Bottom Line While there have been documented links between vitamin B12 deficiency and anxiety, experts still arent sure about the mechanisms behind the association, or whether supplementation will help treat anxiety, especially if youre not vitamin B12 deficient

in contrast, claudin-2, a tight junction protein required for the formation of paracellular water channels that is highly expressed in leaky epithelial tissues, is upregulated in IBDs and promotes inflammation 27,46,47