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Radiofrequency (RF) Thermal Ablation involves the placement of microelectrode arrays and the use of high frequency alternating current (about 100 kHz) to the specific area [256]

This could lead to a novel therapeutic strategy for these diseases and their associated complications, including protection for patients with diabetes and obesity related to COVID-19

In terms of clinical subtypes, UMN-predominant ALS shows greater cortical hypointensity compared to LMN-dominant forms, indicating specificity in iron distribution (342, 343)