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A number of medications, including Interlukin-17 (IL-17) solanezumab, bapineuzumab, avagacestat, and tarenflurbil, have entered clinical trials, although they have not yet shown clinically significant efficacy

(826) Calahorrano-Moreno, M

Bai Y, Li T, Wang Q, You W, Yang H, Xu X, et al

P38 directly phosphorylates the CMA receptor LAMP2A at threonine residues, resulting in its membrane accumulation and conformational activation, and subsequent activation of the CMA pathway (67)