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This review offers an integrative perspective by systematically comparing the efficacy and hepatotoxicity profiles of all approved oral psoriasis therapies while incorporating emerging treatments and pharmacogenomic considerations

Although animal models present challenges in studying NPS, they offer invaluable insights into the potential underlying mechanisms

The intake of non-digestible carbohydrates has been associated with an increase in beneficial bacterial populations, such as lactic acid bacteria, Ruminococcus , Eubacterium rectale , and Roseburia , while concurrently reducing the abundance of potentially harmful species, including Clostridium and Enterococcus (85)

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