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Description

Xu Y, Zhang H, Sun Q, Geng R, Yuan F, Liu B

ACS Nano 2022, 16 (10), 1570515733

Pseudomonas aeruginosa exemplifies an organism that has evolved unusually robust, multi-layered defensesdeploying periplasmic surveillance and export (CopRSPcoBA), cytoplasmic sensing and efflux (CueR-regulated CopA/CzcR regulated CzcCBA system), and an additional small-molecule strategy in which copper is neutralized by sequestration into the organometallic complex fluopsin C