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PLoS ONE 10:e0136468 [DOI] [PMC free article] [PubMed] [Google Scholar] Zhao X et al (2019) Benefits of vitamins in the treatment of Parkinsons disease

This method is often recommended for people who: IM injections provide higher bioavailability compared to oral supplements, meaning the body can utilize the vitamins more effectively

Those with genetic variations on particular B12 pathways may benefit from supplementation with alternative or multiple forms of B12 - including methylcobalamin, adenosylcobalamin or hydroxocobalamin