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Description

Fumarate binds with antioxidant glutathione to produce succinated glutathione (GSF), which is an alternative substrate to glutathione reductase (GR) and downregulates NADPH levels while promoting ROS production [30]

Actual treatments for AD are topical moisturizers, corticosteroids, calcineurin inhibitor, phototherapy, and systemic immunotherapy [113,114,115,116,117,118,120]