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Other groups found similar outcomes that linked the GPx3 locus to ALS but were also able to demonstrate that lower GPx3 levels strongly correlated with more advanced disease, in addition to showing significant motor deficits in a knockdown zebra fish model 21

14 In addition to studies on general aging, animal trials in mice have also evaluated the potential of GHK-Cu treatment in mice with Alzheimers disease

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Cesareo E, Parker LJ, Pedersen JZ et al (2005) Nitrosylation of human glutathione transferase P1-1 with dinitrosyl diglutathionyl iron complex in vitro and in vivo