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this is achieved by the enzymes involved having low substrate specificity

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In a randomized controlled trial, low-dose aspirin improves endothelial cell health in psoriasis via platelet cyclooxygenase-1 (COX-1) inhibition, which reduces the downstream release of membrane-bound arachidonic acid and TxB2(the inactive metabolite of TxA2) (52)

IDH1 gene transcription is sterol regulated and activated by SREBP-1a and SREBP-2 in human hepatoma HepG2 cells: evidence that IDH1 may regulate lipogenesis in hepatic cells