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In a randomized clinical trial comparing oral and parenteral therapy, both groups showed similar reductions in mean corpuscular volume and increases in hematocrit at 4 months.11 The present case highlights the causal relationship between vitamin B12 deficiency and generalized skin hyperpigmentation, an association that presents a wide variety of dermatological manifestations

Wang YL, Han QQ, Gong WQ, Pan DH, Wang LZ, Hu W, Yang M, Li B, Yu J, Liu Q

The virus utilizes the ACE2 receptor to enter and infect intestinal epithelial cells