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In comparison, rhGPx3 mutant seems more likely to catalyze the reaction just like GPx4, which is the only monomeric member among the GPx family, due to the fact that the mutant exists as a monomer in its native state

and increases GPX4, Wnt1, and -catenin levels, implicating the Wnt/-catenin pathway in EA-mediated neuroprotection (164)

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