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2015;51C:1007

For references and more information , see the section on Cardiovascular disease in the Folate article

Tirapazamine suppress osteosarcoma cells in part through slc7a11 mediated ferroptosis

The approval is backed by data from Part 1 of the Phase III RUBY trial, where treatment with the Jemperli regimen led to a 31% reduction in risk of death compared to chemotherapy alone