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Mediterr J Hematol Infect Dis 6(1):e2014006 Talpaz M, Kantarjian H, Kurzrock R, Trujillo JM, Gutterman JU (1991) Interferon-alpha produces sustained cytogenetic responses in chronic myelogenous leukemia: Philadelphia chromosome-positive patients

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To test functionality and dynamic range of secreted roGFP2-Orp1, we fully reduced and oxidised the sensor protein in vivo , using the reductant dithiothreitol (DTT) and the thiol-specific oxidant 2,2-dipyridyl disulfide (DPS) (Lopez-Mirabal et al ., 2007)