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These models have provided a service in the development of therapies for Graves disease, including immune-modulatory treatments targeting autoimmune components of the disease, and thus laid the groundwork for therapeutic advances in human patients (Kahaly 2020)

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J Physiol Pharmacol 65(1):1523 Jiang T, Zhang W, Wang Z (2020) Laquinimod protects against tnf--induced attachment of monocytes to human aortic endothelial cells (HAECs) by increasing the expression of KLF2