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Hepatology 59 , 13931405 (2014)

10.1016/s0531-5565(01)00204-2 50 DuongT.GallagherK

CYP2E1 and CYP1A2 enzymes metabolize a tiny percentage (about 5%), resulting in NAPQI, a hazardous byproduct that is typically removed by glutathione (GSH)