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As explained above, the present invention relates to the treatment or prevention of diabetes, obesity, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis (NASH), a cardiovascular disease or any other disease/disorder involving GLP-1 (including any disease/disorder involving, or mediated by, a deficiency of GLP-1 or deficient GLP-1 signalling), using the solid oral pharmaceutical composition provided herein

Therefore, Fangs team [56, 58] constructed a heterologous expression system based on genetic engineering for Bacillus cereus to obtain stable collagenase for preparing the collagen hydrolysate with high antioxidant activity

The microneedling evidence base is for delivering established hair compounds a randomized pilot of microneedling plus minoxidil (PMID 23960389) reported greater hair-count change than minoxidil alone, and a 2025 study of copper-peptide microneedling for androgenetic alopecia (PMID 40225275) reported measurable regrowth neither study tested AHK-Cu as a standalone topical

The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37C for 48h, and no obvious degradation and precipitation were observed