l carnitine and exercise intolerance Carnitine: Genetic Variants Affecting Mitochondrial Energy Health From brain to muscle, L-Carnitine

Metabolism 142 , 155433 (2023)

Although various studies on copper-induced cell death have shown promising results, there still remain several challenges, such as how the aggregation of fatty acylated proteins triggers cell death, optimizing the performance of copper regulators and reducing their side effects, determining the mode of death induced by copper overload and deficiency, gaining a comprehensive understanding of the roles of copper in the mitochondria, and whether copper ion carriers can selectively deliver drugs to hypertrophic myocardial tissues through drug delivery systems (183)

1.9 Treatment 1.9.1 Supportive treatment Although effective antidotes are available, general supportive measures should not be ignored and may be life-saving

[DOI] [PubMed] [Google Scholar] Zawada J