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Anti-CCP is far more specific for rheumatoid arthritis than rheumatoid factor and can be positive years before clinical disease

Furthermore, the authors validated the capacity of MnO 2 -coated mesoporous silica nanoparticles (MSNs) to control drug release, and the camptothecin (CPT)-loaded MnO 2 -MSNs showed sustained CPT release after the addition of GSH (Figure 1G)