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GSH is primarily synthesized in liver, and decreased levels of circulating GSH have been reported in liver diseases, including metabolic dysfunctionassociated steatotic liver disease (MASLD) and metabolic dysfunctionassociated steatohepatitis (MASH) (4, 5)

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manufactured by Diagen, d.o.o., Ljubljana, Slovenia) (9-11, 13-24), morphine Merck 20 (Merck KGaA, Darmstadt, Germany), naloxone hydrochloride (Sigma-Aldrich, Germany), haloperidol (Sigma-Aldrich, Germany) were used