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JW: Writing review & editing

Funding Statement: None

It should be noted that experimental studies show that SARS-CoV-2 can infect immune cells, with preference to activated T-cells in an ACE2-R-independent manner and cause apoptosis of T-cells associated with mitochondria-ROS-hypoxia pathways [155]

Many of these raw materials contain significant amounts of glutamate, which can be utilized by LAB to convert glutamate to GABA using the GAD enzyme to increase tolerance to acidic conditions 57