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No high-quality clinical trial has demonstrated that B12 injections produce meaningful weight loss outcomes independent of dietary and exercise changes

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They ate around it, but the med itself. Additionally, there are concerns about chewables being too appealing, as another owner expressed worry that their dog could accidentally ingest a large quantity if left within reach, describing how the tablets [are] yummy on purpose, which is great for ease of administration, but it can obviously cause problems. The slightly mixed reception highlights the balance between making medications palatable and ensuring safe administration practices among pet owners

PMID: 34170647